The intelligence layer for 800Mliving with autoimmune disease.
BuddyRise turns continuous real-world signals into personalized action while building the longitudinal autoimmune record healthcare never had.
Medicine treats autoimmune disease in fifteen-minute snapshots.
An autoimmune patient sees a specialist three or four times a year. The disease happens every day in between. Symptoms, triggers, flares, the effect of sleep, stress, and food go uncaptured. Care is built on what a patient can recall in a short visit months apart. It is reactive, generic, and late.
Autoimmunity is the largest unclaimed chronic disease category.
Annual US economic burden for treatment. $12K–$100K+ per patient per year, of which biologics for autoimmune and rare conditions are the fastest rising — some now exceeding $60K annually.
Autoimmunity moves with daily life, so the intervention has to live there too.
Immunity is written by environment, not genome
Brodin et al., Cell 2015
Specific exposures are causal triggers
Bjornevik et al., Science 2022
Change the inputs, the disease changes
Agrawal et al. · Levine et al. 2019
So the science points to a daily companion
BuddyRise closes the loop
The pieces finally fit together.
Autoimmunity is now recognized as multifactorial
Research confirms the role of lifestyle, environment, stress, sleep, nutrition and hormones in disease progression.
Wearables & AI make continuous personal intelligence possible
Wearables, sensors and AI make it possible to continuously track relevant signals at scale and turn it into personal guidance.
People are ready for proactive, personalized care
71% US adults use health apps showing people want to be active partners in their health.
For the first time, continuous autoimmune intelligence is possible.
First NIH-wide Immune Disease Research Strategic Plan (2026 – 2030).
Lived experience. Technical execution. Clinical authority.
Living with autoimmunity. From Bedbound MS to remission. Founder of Futurethos Consulting; 5 years in AI ethics & governance across UNESCO, the EU Commission, MILA, and the FARI AI Institute, focused on health and medtech. Bootstrapped BuddyRise from 0 to 5.0× organic user growth before spending a dollar on paid acquisition, first VC investment, close first clinical trial.
LinkedIn
Full-stack developer & neuroscientist with a behavioral science focus, studying social digital behavior patterns. King's College London, UN and the Belgian Mission. Built and shipped BuddyRise's product, app, AI engine, gamification, and data infrastructure solo through launch and user growth.
LinkedIn
Principal Investigator on BuddyRise's clinical research. Founder of Thrive85, a longevity clinic built on the same lifestyle-medicine thesis as BuddyRise. Trained at Cleveland Clinic and Harvard Medical School. Board member, ERN RECONNET, Europe's lupus reference network.
LinkedIn
BuddyRise connects the dots.
A lifelong companion that starts as an app and becomes the world's largest longitudinal autoimmune dataset.
Log your daily life
Find patterns & get a personal daily plan that adapts.
Your pain and fatigue rose as both patterns overlapped
Your symptom severity averaged 6.1 this week, up from 5.0 last week. We noticed more stress, less sleep, and that your cycle is in the luteal phase. You also logged fewer nourishing meals and less breathwork than usual. This may be a useful pattern to watch.
Work with your medical team
Pattern spotted: short sleep + heat → fatigue spike 1–2 days later. Seen 5×.
Our longitudinal moat
Every interaction writes to one continuous patient record
This gap compounds daily, starting from day one. We're 75 days in — but every day we operate is a day of record a later competitor can never recover. A late start isn't something speed can fix; the lead only widens from here.
A retention loop built into every day.
A daily AI plan built around the user
Every action builds progress
Consistency becomes social
AI buddy Launch, 75 days: +5000 patients, $0 CAC
activate — finish onboarding, talk to Buddy
come back week 1 — above industry benchmark
AI action-plan home screen and rise up challenges ships September
A sequenced path to $100M+ ARR
The app is the entry point. The intelligence layer is the business.
Daily use, retention and willingness to pay.
Paid populations once engagement is proven.
Validated impact and cost-of-care reduction.
Longitudinal evidence at scale.
How we scale to 1M paying users.
Proven organic traction. Scalable acquisition. Enterprise distribution.
Other categories produced decacorns, autoimmunity is still up for grabs.
¹ Hinge and Omada figures are projected 2026 revenue.
No one owns the daily intelligence layer in autoimmunity.
Existing solutions solve pieces of the journey. BuddyRise connects daily-life data, autoimmune context and adaptive action in one continuous system.
& adaptive
& reactive
+ continuous + adaptive
& care programs
but limited scale
& lifestyle apps
trackers / symptom apps
but not adaptive
Autoimmune-native intelligence
Daily signals interpreted through autoimmune context.
Continuous learning loop
Track → understand → act → learns what works for each person.
Consumer engagement + longitudinal data
A daily product designed to compound personalization over time.
We're not raising yet.
We're opening the round in Q4.
Bootstrapping traction now, opening the round in Q4. Early conversations start today.
In the press.
Contact.
- charline@buddyrise.com
- Based in
- Ghent, Belgium · San Francisco, US